Immune System News

April 18, 2024

Top Headlines

How the Body Switches out of 'Fight' Mode

Apr. 10, 2024 — Cortisone and other related glucocorticoids are extremely effective at curbing excessive immune reactions. But previously, astonishingly little was known about how they exactly do that. Researchers have now explored the molecular mechanism of action ...

New Drug Prevents Flu-Related Inflammation and Lung Damage

Apr. 10, 2024 — Findings show a newly created drug can prevent runaway inflammation while still allowing the immune system to handle the virus, even when given late into ...

Respiratory Allergies: Newly Discovered Molecule Plays a Major Role in Triggering Inflammation

Apr. 10, 2024 — One of the molecules responsible for triggering the inflammation that causes allergic respiratory diseases, such as asthma and allergic rhinitis, has just been discovered. This molecule, from the ...

Hope for Treating Autoimmune Diseases

Apr. 3, 2024 — A routine blood test that measures a patient's inflammation levels could improve the early diagnosis and management of a wide range of debilitating autoimmune diseases. The Systemic Inflammation Index (SII) uses information from routine laboratory ...

Latest Headlines

updated 9:45pm EDT

Siblings With Unique Genetic Change Help Scientists Progress Drug Search for Type 1 Diabetes

Apr. 18, 2024 — Two siblings who have the only known mutations in a key gene anywhere in the world have helped scientists gain new insights that could help progress ...

Scientists Identify Pro-Aging 'Sugar Signature' in the Blood of People Living With HIV

Apr. 10, 2024 — Scientists have identified sugar abnormalities in the blood that may promote biological aging and inflammation in people living with ...

Researchers Identify Protein That Controls CAR T Cell Longevity

Apr. 10, 2024 — CAR T cell therapy has revolutionized the way certain types of cancer are treated, and the longer those CAR T cells live in a patient's body, the more effectively they respond to cancer. Now, ...

Gene Analysis Generates Spatial Map of Intestinal Cells and Traces Their Trajectories During Gut Inflammation

Apr. 2, 2024 — Cells within the intestines perform various roles including nutrient absorption, sensing, and maintaining homeostasis. Certain chronic disorders are ...

New Research Offers Insight Into the Future Understanding of MS and Its Treatments

Apr. 4, 2024 — Researchers have developed a new and unique blood test to measure the immune response to the Epstein Barr Virus (EBV) which is the leading risk ...

Mitochondrial Roles in Antiviral Immunity Modify Manifestations of Neurological Diseases

Apr. 4, 2024 — Scientists report that a progressive neurodegenerative disease can be triggered by a viral infection. The mechanism relates to mitochondrial roles in ...

Discovery Into How Chronic Lung Conditions Affect Children's Immune System

Apr. 4, 2024 — Researchers have made a breakthrough into how two chronic respiratory diseases in childhood affect the immune system, paving the way for better ...

Treatment With Anti-Inflammatory Proteins Following Heart Attack Shows Promise to Reduce the Risk of Further Heart Damage

Apr. 4, 2024 — Research into the protective effects of two anti-inflammatory molecules, transforming growth factor-beta1 (TGF 1) and Heligmosomoides polygyrus TGM ...

Immunotherapy for Alzheimer's Disease Shows Promise in Mouse Study

Apr. 3, 2024 — Scientists have shown that treating mice with an antibody that blocks the interaction between APOE proteins (white) sprinkled within Alzheimer's disease plaques and the LILRB4 receptor on microglia ...

Scientists Pioneer Immunotherapy Technique for Autoimmune Diseases

Apr. 1, 2024 — Scientists have developed an immunotherapy strategy that potentially lays the groundwork for treating a spectrum of autoimmune ...

New Insights Could Unlock Immunotherapy for Rare, Deadly Eye Cancer

Apr. 16, 2024 — New research explains why metastatic uveal melanoma is resistant to conventional immunotherapies and how adoptive therapy, which involves growing a patient's T cells outside the body before ...

Investigators Develop Novel Treatment for T-Cell Leukemias and Lymphomas

Apr. 2, 2024 — A novel treatment for leukemias and lymphomas that arise from immune system T cells was found to be effective at killing these cancers in mice bearing human T-cell ...

'Exhausted' Immune Cells in Healthy Women Could Be Target for Breast Cancer Prevention

Mar. 28, 2024 — People carrying BRCA1 and BRCA2 gene mutations are at high risk of developing breast and ovarian cancer. Researchers have found that changes occur in the immune cells of breast tissue in carriers of ...

A Combination of Approved Drugs Enhances the Delivery of Anti-Bacterial Medications to Treat Tuberculosis

Mar. 27, 2024 — Researchers have found that approved drugs that were originally shown to normalize blood vessels surrounding tumors (to improve drug delivery to cancer cells) can enhance the delivery of ...

Making Long-Term Memories Requires Nerve-Cell Damage

Mar. 27, 2024 — Just as you can't make an omelet without breaking eggs, scientists have found that you can't make long-term memories without DNA damage and brain ...

Researchers Create Biocompatible Nanoparticles to Enhance Systemic Delivery of Cancer Immunotherapy

Mar. 27, 2024 — Researchers are enhancing immunotherapy effects against malignant tumors by developing and validating patent-ending poly (lactic-co-glycolic acid), or PLGA, nanoparticles modified with adenosine ...

Old Immune Systems Revitalized in Mouse Study, Improving Vaccine Response

Mar. 27, 2024 — Those with aging immune systems struggle to fight off novel viruses and respond weakly to vaccination. Researchers were able to revitalize the immune system in ...

Researchers a Step Closer to a Cure for HIV

Mar. 26, 2024 — A new study shows virus-like particle can effectively 'shock and kill' latent HIV reservoir in those living with chronic ...

Genetically Engineered Dendritic Cells Enhance the Power of Immunotherapy Against Lung Cancer

Mar. 26, 2024 — A new study suggest that using CXCL9 and CXCL10-producing dendritic cells alongside immunotherapy can be a promising strategy to overcome treatment resistance and improve clinical outcomes for ...

Gene Discovery Offers New Hope for People Living With Chronic Skin Disease

Mar. 25, 2024 — Scientists have discovered a gene mutation is responsible for causing psoriasis -- a chronic inflammatory skin disease that causes patients to develop red, scaly and itchy patches across their body. ...

An Immunotherapy to Overcome Resistant Leukemia

Mar. 21, 2024 — Researchers have discovered that a specific mutation in the cancer cells of an aggressive type of blood cancer can prevent novel immunotherapies such as CAR T-cell therapy from working. Their study ...

Immune Cells Identified as Key Players in Brain Health

Mar. 21, 2024 — Using novel genetic and genomic tools, researchers have shed light on the role of immune cells called macrophages in lipid-rich tissues like the brain, advancing our understanding of Alzheimer's ...

Severe Lung Infection During COVID-19 Can Cause Damage to the Heart

Mar. 20, 2024 — SARS-CoV-2, the virus that causes COVID-19, can damage the heart even without directly infecting the heart tissue, a new study has found. The research specifically looked at damage to the hearts of ...

Cellular Architecture of Lesions in Multiple Sclerosis Now Mapped out

Mar. 20, 2024 — Using advanced methodology, scientists have been able to reveal at the cellular level how lesions in multiple sclerosis ...

Heat Exposure May Increase Inflammation and Impair the Immune System

Mar. 20, 2024 — Exposure to high heat may impair the cells of the immune system that remember specific viruses and germs and over-produce signaling molecules that can lead to ...

Empty 'Backpacks' Activate the Immune System Against Cancer

Mar. 19, 2024 — Researchers have discovered that the mere act of attaching their microparticle 'backpacks' to neutrophils is enough to activate them against cancer -- no drugs needed. In experiments, ...

How Cells Are Ahead of the Curve

Mar. 18, 2024 — The curvature of a surface determines the migration behavior of biological cells. They preferentially move along valleys or grooves while avoiding ridges. These findings gave rise to a model ...

Researchers Identify a Signaling Molecule in Neuroblastoma Immunosuppression and Aggressiveness

Mar. 15, 2024 — The MYCN oncoprotein plays a key role in starting, advancing and making it difficult to treat various human cancers. When MYCN is overactive, especially in high-risk neuroblastoma, the tumors become ...

Key Metabolic Process Responsible for Rapid Immune Responses Discovered

Mar. 15, 2024 — Researchers identified a key metabolite in cells that helps direct immune responses and explains at a single cell level why immune cells that most efficiently recognize pathogens, vaccines, or ...

Gut Bacteria Make Neurotransmitters to Shape the Newborn Immune System

Mar. 15, 2024 — Investigators discovered that unique bacteria colonize the gut shortly after birth and make the neurotransmitter serotonin to educate gut immune cells. This prevents allergic reactions to food and ...